Dedicated to Professor Brindaban C. Ranu on his 75th birthday.
Abstract
Mechanochemistry, a solvent-free approach that harnesses mechanical energy, is emerging
as a transformative technique in modern chemistry. It has emerged from a niche technique
to a versatile tool with broad applications. By inducing physical and chemical transformations,
it enables the synthesis of complex molecules and nanostructured materials. Recent
advancements have extended its applications beyond simple physical transformations
to encompass catalytic processes, unlocking new possibilities for selective synthesis
and product design. This account delves into the fundamentals of mechanochemistry
and its applications in organic synthesis, also beyond traditional synthetic routes.
Mechanochemistry offers new avenues for molecular and materials discovery, expanding
the scope of accessible chemical space.
1 Introduction
2 Organic Synthesis in Ball Mills
3 Combination with Different Energy Sources
4 Advantages of Mechanochemistry
5 Future of Mechanochemistry
6 Conclusion
Key words
mechanochemistry - organic synthesis - solvent-free reactions - catalysis - green
chemistry
