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Klin Monbl Augenheilkd 2025; 242(01): 7-21
DOI: 10.1055/a-2327-8597
Übersicht

Differenzialdiagnose der altersabhängigen Makuladegeneration

Article in several languages: English | deutsch

Authors

  • Peter Charbel Issa 

    1   Augenklinik, Klinikum rechts der Isar, Technische Universität München, Deutschland
    2   Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

  • Samantha R. De Silva 

    2   Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

  • Kristina Pfau

    3   Augenklinik, Universitätsspital Basel, Schweiz

  • Johannes Birtel 

    2   Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
    4   Klinik für Augenheilkunde, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland
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Erratum: Differentialdiagnose der Altersabhängigen MakuladegenerationKlin Monbl Augenheilkd 2025; 242(01): e1-e1
DOI: 10.1055/a-2524-5086

Zusammenfassung

Die Diagnose der altersabhängigen Makuladegeneration (AMD) kann einen Einschnitt im Leben von Patienten bedeuten. Vor diesem Hintergrund ist es wichtig, Differenzialdiagnosen in Erwägung zu ziehen, da diese sich hinsichtlich Prognose, Vererblichkeit, Kontroll- und Therapiebedarf beträchtlich von der AMD unterscheiden können. Differenzialdiagnosen sind vor allem andere Makulaerkrankungen mit Drusen, drusenähnlichen Veränderungen, weitere monogene Netzhautdystrophien sowie ein breites Spektrum weiterer, oftmals seltener Makulaerkrankungen. In dieser Übersicht werden anhand klinischer Beispiele Befundkonstellationen gezeigt, bei denen eine Differenzialdiagnose der AMD in Erwägung gezogen werden sollte. Unter anderem beinhaltet dies Patienten mit autosomal-dominanten Drusen, Sorsby-Fundusdystrophie, Pachydrusen, spät beginnendem Morbus Stargardt, extensive makuläre Atrophie mit Pseudodrusen (EMAP), Pseudoxanthoma elasticum (PXE), North-Carolina-Makuladystrophie, mitochondriale Retinopathie, Benign Yellow Dot Maculopathy, kuppel- oder leistenförmige Makulopathie und makuläre Teleangiektasien Typ 2.

Schlüsselwörter

altersabhängige Makuladegeneration - AMD - Differenzialdiagnose - multimodale Bildgebung


Publication History

Received: 19 February 2024

Accepted: 08 May 2024

Article published online:
16 January 2025

© 2025. Thieme. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

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