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Klin Monbl Augenheilkd 2023; 240(09): 1052-1059
DOI: 10.1055/a-2105-1064
Übersicht

Age-Related Macular Degeneration in an Ageing Society – Current Epidemiological Research

Article in several languages: English | deutsch

Authors

  • Caroline Brandl 

    1   Universitäts-Augenklinik Regensburg, Universität Regensburg, Fakultät für Medizin, Deutschland
    2   Lehrstuhl für Genetische Epidemiologie, Universität Regensburg, Fakultät für Medizin, Deutschland

  • Robert Patrick Finger

    3   Universitäts-Augenklinik, Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim, Ruprecht-Karls-Universität Heidelberg, Mannheim, Deutschland
    4   Universitäts-Augenklinik Bonn, Universität Bonn, Deutschland

  • Iris Maria Heid

    2   Lehrstuhl für Genetische Epidemiologie, Universität Regensburg, Fakultät für Medizin, Deutschland

  • Matthias Marten Mauschitz

    4   Universitäts-Augenklinik Bonn, Universität Bonn, Deutschland
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Abstract

Epidemiological studies on age-related macular degeneration (AMD) provide crucial data on the frequency of early and late forms as well as associated risk factors. The increasing number of population-based cross-sectional and longitudinal cohort studies in Germany and Europe with published data is making prevalence and incidence estimators for AMD more robust, although they show mostly method-related fluctuations. This review article brings together the latest published epidemiological measures for AMD from Germany and Central as well as Western Europe. Based on this data and population figures for Germany and Europe, prevalence is projected, and future trends are forecasted. The epidemiological evidence for AMD-associated risk factors is also improving, especially through meta-analyses within large consortia with correspondingly high case numbers. This review article summarizes the latest findings and resulting recommendations for prevention approaches. Additionally, it discusses treatment options and future challenges.

Key words

age-related macular degeneration (AMD) - prevalence - incidence - risk factors - population-based studies - demographic development


Publication History

Received: 26 April 2023

Accepted: 22 May 2023

Article published online:
04 September 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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