Cutting into the black sea: endoscopic submucosal dissection using a clip with line for a rectal polyp with severe fibrosis after tattooing

A 75-year-old woman underwent a follow-up colonoscopy after polypectomy of colorectal adenomas. A 20-mm polyp with submucosal invasion was diagnosed endoscopically in the lower rectum, marked with tattoo, and the patient was then referred to our institute for surgery.

Colonoscopy revealed a 20-mm reddish protruding lesion with tattooing laterally on both sides of the lesion ([Fig. 1]). The macroscopic type was 0-Is, the Japanese Narrow-Band Imaging Expert Team classification was type 3, and the pit pattern was VN, suggesting submucosal invasion. As the patient did not wish a stoma to be made, endoscopic submucosal dissection (ESD) was attempted, and she was enrolled in a clinical trial (JCOG1612) investigating the efficacy of chemoradiation after local resection of rectal cancer [1].

Fig. 1 A 20-mm reddish protruding lesion in the lower rectum with tattooing on both lateral sides of the lesion.

After injecting the anal side, where the effect of the prior tattooing was minimal, we made a mucosal incision and a flap ([Fig. 2]), revealing black submucosa together with severe fibrosis ([Video 1]). A clip with line ([Fig. 3]) [2] enabled good visibility of the cutting layer. We finally managed to complete resection in 62 minutes. Black tissue was spread almost all over the submucosa ([Fig. 4]) on the vertical side. The pathological diagnosis was 16 × 15 mm, tub1 > tub2, pT1b (SM: 4000 μm), INFb, Ly0 (D2–40), V1 (EVG) (SM), BD1, Pn0, HM0, VM0. Severe fibrosis with black staining was identified pathologically ([Fig. 5]).

Fig. 2 A flap made from the anal side, where the effect of prior tattooing was minimal.

Video 1 Cutting into the black sea: endoscopic submucosal dissection using a clip with line for a rectal polyp with severe fibrosis after tattooing.

Fig. 3 A clip with line attached to get adequate tension for good visibility of the submucosal layer.

Fig. 4 Vertical view of the resected specimen showing black tissue spread over almost all of the submucosa after en bloc resection.

Fig. 5 Severe fibrosis with black staining was identified pathologically.

Endoscopic resection is sometimes performed after tattooing, because the preoperative diagnosis of the invasion depth is different from that at the previous hospital, or for submucosal invasive cancer together with subsequent chemoradiotherapy [1]. Although severe fibrosis and black submucosa have led to difficulty in finding the appropriate cutting plane and achieving en bloc resection [3], successful ESD by conventional [4] or tissue retractor system-assisted methods [5] have been reported. By using the clip with line, which is an easy and inexpensive method, successful ESD was achieved in the present case.

Endoscopy_UCTN_Code_TTT_1AQ_2AD

Publication History

Article published online:
16 January 2023

• References

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