Formal Syntheses of Dictyodendrins B, C, and E by a Multi-Substituted Indole Synthesis

Abstract

The dictyodendrins are a family of marine alkaloids, which possess a highly substituted pyrrolo[2,3-c]carbazole core. This core structure can be regarded as a multi-substituted indole and aniline moiety. To achieve a concise synthesis of dictyodendrins, we planned to capitalize on our previously developed multi-substituted indole synthesis. By using this method along with two C–H functionalizations, formal syntheses of dictyodendrins B, C, and E were achieved.

Key words

dictyodendrins - C–H functionalization - [4+2] cycloaddition - ynamide - indole

• References

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