Retinal Vasculitis Case Developing in the Early Period after COVID-19Retinaler Vaskulitisfall, der sich in der frühen Phase nach COVID-19 entwickelt
Coronavirus disease (COVID-19) is a new disease that can potentially be fatal and affect the lungs and airways. The virus is thought to be most likely transmitted by an interspecies jump from bats to intermediate hosts and from animal hosts to humans . COVID-19, which is highly contagious and often manifests itself with fever, cough, weakness, muscle pain, and shortness of breath, is thought to be transmitted mainly through droplets in the environment as a result of contact with infected patients , . It has been reported that COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which infects host cells using renin angiotensin-converting enzyme 2 (ACE2) receptors, which are widely expressed in the body, causes tissue hypoperfusion and thrombosis in different stages of the disease by causing endothelial cell inflammation and dysfunction , , , .
In this study, we aimed to present a case that developed retinal vasculitis in the early period after a SARS-CoV-2 infection, which causes COVID-19.
Received: 07 November 2020
Accepted: 17 January 2021
14 April 2021 (online)
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- 1 Ashour HM, Elkhatib WF, Rahman MM. et al. Insights into the recent 2019 novel coronavirus (Sars-coV-2) in light of past human coronavirus outbreaks. Pathogens 2020; 9: 186 doi:10.3390/pathogens9030186
- 2 Fan Q, Zhang W, Li B. et al. Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan. Front Cell Infect Microbiol 2020; 10: 404 doi:10.3389/fcimb.2020.00404
- 3 Van Doremalen N, Bushmaker T, Morris DH. et al. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med 2020; 382: 1564-1567 doi:10.1056/NEJMc2004973
- 4 Casagrande M, Fitzek A, Püschel K. et al. Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients. Ocul Immunol Inflamm 2020; 28: 721-725 doi:10.1080/09273948.2020.1770301
- 5 Becker RC. COVID-19 update: Covid-19-associated coagulopathy. J Thromb Thrombolysis 2020; 50: 54-67 doi:10.1007/s11239-020-02134-3
- 6 Varga Z, Flammer AJ, Steiger P. et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet 2020; 395: 1417-1418 doi:10.1016/S0140-6736(20)30937-5
- 7 Carnevale S, Beretta P, Morbini P. Direct endothelial damage and vasculitis due to SARS-CoV-2 in small bowel submucosa of COVID-19 patient with diarrhea. J Med Virol 2020; DOI: 10.1002/jmv.26119.
- 8 Seah I, Agrawal R. Can the Coronavirus Disease 2019 (COVID-19) Affect the Eyes? A Review of Coronaviruses and Ocular Implications in Humans and Animals. Ocul Immunol Inflamm 2020; 28: 391-395 doi:10.1080/09273948.2020.1738501
- 9 Wang Y, Detrick B, Yu ZX. et al. The role of apoptosis within the retina of coronavirus-infected mice. Invest Ophthalmol Vis Sci 2000; 41: 3011-3018
- 10 Marinho PM, Marcos AAA, Romano AC. et al. Retinal findings in patients with COVID-19. Lancet 2020; 395: 1610 doi:10.1016/S0140-6736(20)31014-X
- 11 Sheth JU, Narayanan R, Goyal J. et al. Retinal vein occlusion in COVID-19: A novel entity. Indian J Ophthalmol 2020; 68: 2291-2293 doi:10.4103/ijo.IJO_2380_20
- 12 Lalitha P, Rathinam S, Banushree K. et al. Ocular involvement associated with an epidemic outbreak of chikungunya virus infection. Am J Ophthalmol 2007; 144: 552-556 doi:10.1016/j.ajo.2007.06.002
- 13 Chan DPL, Teoh SCB, Tan CSH. et al. Eye Institute Dengue-Related Ophthalmic Complications Workgroup. Ophthalmic complications of dengue. Emerg Infect Dis 2006; 12: 285-289 doi:10.3201/eid1202.050274
- 14 Marinho PM, Marcos AAA, Romano AC. et al. Retinal findings in patients with COVID-19. Lancet 2020; 395: 1610 doi:10.1016/S0140-6736(20)31014-X