Klin Monbl Augenheilkd
DOI: 10.1055/a-1353-5915
Der interessante Fall

Bilateral Central Retinal Artery Occlusion Secondary to SARS-CoV-2 Infection in the Early and Late Periods: A Case Report

Bilateraler Verschluss der zentralen Netzhautarterie als Folge von SARS-CoV-2 in der frühen und späten Periode: Fallbericht
Mine Karahan
Ophthalmology, Dicle Üniversitesi Tip Fakültesi, Diyarbakir, Turkey
,
Ophthalmology, Dicle Üniversitesi Tip Fakültesi, Diyarbakir, Turkey
,
Leyla Hazar
Ophthalmology, Dicle Üniversitesi Tip Fakültesi, Diyarbakir, Turkey
,
Mehmet Emin Dursun
Ophthalmology, Dicle Üniversitesi Tip Fakültesi, Diyarbakir, Turkey
,
Sedat Ava
Ophthalmology, Dicle Üniversitesi Tip Fakültesi, Diyarbakir, Turkey
,
Huseyin Emek
Ophthalmology, Dicle Üniversitesi Tip Fakültesi, Diyarbakir, Turkey
,
Ugur Keklikci
Ophthalmology, Dicle Üniversitesi Tip Fakültesi, Diyarbakir, Turkey
› Author Affiliations

Background

The causative agent of coronavirus disease (COVID-19) is a new virus termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the coronavirus family. It was first detected in China in December 2019 and spread rapidly around the world. COVID-19 is highly contagious and mainly transmitted through contact with infected patients or droplets. The most common symptoms are fever, cough, weakness, muscle pain, and shortness of breath [1]. SARS-CoV-2 infects host cells through the renin angiotensin-converting enzyme 2 (ACE2) receptors. The ACE2 receptor is widely expressed in many organs, including the retina, and plays a role in the pathogenesis of systemic vascular diseases, which can lead to ocular symptoms such as diabetic and hypertensive retinopathy [2], [3]. SARS-COV-2 has been reported to be associated with neurological symptoms, including stroke, thromboembolism (e.g., pulmonary embolism), and myocardial infarction. Hypercoagulation associated with COVID-19 has been described as “sepsis-induced coagulopathy” and may predispose patients to the spectrum of thromboembolic events [4], [5], [6].

We present here the first case of bilateral central retinal artery occlusion (CRAO) that developed in the early and late stages secondary to the SARS-CoV-2 infection.



Publication History

Received: 15 November 2020

Accepted: 05 January 2021

Publication Date:
19 February 2021 (online)

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