Klin Monbl Augenheilkd 2020; 237(10): 1172-1176
DOI: 10.1055/a-1264-8048
Übersicht

Digital and Technical Developments in the Amblyopia Therapy

Article in several languages: English | deutsch
Charlotte Schramm
1   Universitäts-Augenklinik, Universitätsklinikum Tübingen, Deutschland
,
Yaroslava Wenner
2   Klinik für Augenheilkunde, Universitätsklinikum der Goethe-Universität Frankfurt, Deutschland
› Author Affiliations

Abstract

The digital media becomes more and more common in our everyday lives. So it is not surprising that technical progress is also leaving its mark on amblyopia therapy. New media and technologies can be used both in the actual amblyopia therapy or therapy monitoring. In particular in this review shutter glasses, therapy monitoring and analysis using microsensors and newer video programs for amblyopia therapy are presented and critically discussed. Currently, these cannot yet replace classic amblyopia therapy. They represent interesting options that will occupy us even more in the future.



Publication History

Received: 16 June 2020

Accepted: 16 September 2020

Article published online:
15 October 2020

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  • References/Literatur

  • 1 Elflein HM, Fresenius S, Lamparter J. et al. Amblyopieprävalenz in Deutschland. Daten aus der prospektiven, populationsbasierten Gutenberg-Gesundheitsstudie. Dtsch Arztebl Int 2015; 112: 338-344
  • 2 Williams C. Amblyopia. BMJ Clin Evid 2009; 2009: 0709
  • 3 Von Noorden GK. Classification of amblyopia. Am J Ophthalmol 1967; 63: 238-244
  • 4 Hess RF, Holliday IE. The spatial localization deficit in amblyopia. Vision Res 1992; 32: 1319-1339
  • 5 Fronius M. Dynamik der visuellen Wahrnehmungsverzerrungen bei Kindern mit Schielamblyopie unter dem Einfluss von Schieloperation und Okklusionstherapie. Klin Monbl Augenheilkd 2006; 223: 52-58
  • 6 von Noorden GK, Crawford ML. The sensitive period. Trans Ophthalmol Soc U K 1979; 99: 442-446
  • 7 Hubel DH, Wiesel TN. The period of susceptibility to the physiological effects of unilateral eye closure in kittens. J Physiol 1970; 206: 419-436
  • 8 Fronius M, Cirina L, Ackermann H. et al. Efficiency of electronically monitored amblyopia treatment between 5 and 16 years of age: new insight into declining susceptibility of the visual system. Vision Res 2014; 103: 11-19
  • 9 Gusek-Schneider GC. Hochgradige Amblyopie – Literaturreview. Klin Monbl Augenheilkd 2011; 228: 859-863
  • 10 Dean SE, Povey RC, Reeves J. Assessing interventions to increase compliance to patching treatment in children with amblyopia: a systematic review and meta-analysis. Br J Ophthalmol 2016; 100: 159-165
  • 11 Wu C, Hunter DG. Amblyopia: diagnostic and therapeutic options. Am J Ophthalmol 2006; 141: 175-184
  • 12 Loudon SE, Simonsz HJ. The history of the treatment of amblyopia. Strabismus 2005; 13: 93-106
  • 13 Sattler CH. Experiences with the elimination of amblyopia and the restoration of binocular vision in squinters, part I. 1927. Strabismus 2009; 17: 90-93
  • 14 Hubel DH, Wiesel TN. Effects of monocular deprivation in kittens. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol 1964; 248: 492-497
  • 15 Chen PL, Chen JT, Tai MC. et al. Anisometropic amblyopia treated with spectacle correction alone: possible factors predicting success and time to start patching. Am J Ophthalmol 2007; 143: 54-60
  • 16 Stewart CE, Moseley MJ, Fielder AR. et al. Refractive adaptation in amblyopia: quantification of effect and implications for practice. Br J Ophthalmol 2004; 88: 1552-1556
  • 17 Stewart CE, Wallace MP, Stephens DA. et al. The effect of amblyopia treatment on stereoacuity. J AAPOS 2013; 17: 166-173
  • 18 Spierer A, Raz J, Benezra O. et al. Treating amblyopia with liquid crystal glasses: a pilot study. Invest Ophthalmol Vis Sci 2010; 51: 3395-3398
  • 19 Wang J, Neely DE, Galli J. et al. A pilot randomized clinical trial of intermittent occlusion therapy liquid crystal glasses versus traditional patching for treatment of moderate unilateral amblyopia. J AAPOS 2016; 20: 326-331
  • 20 Fielder AR, Auld R, Irwin M. et al. Compliance monitoring in amblyopia therapy. Lancet 1994; 343: 547
  • 21 Simonsz HJ, Polling JR, Voorn R. et al. Electronic monitoring of treatment compliance in patching for amblyopia. Strabismus 1999; 7: 113-123
  • 22 Chopovska Y, Loudon SE, Cirina L. et al. Electronic recording of occlusion treatment for amblyopia: potential of the new technology. Graefes Arch Clin Exp Ophthalmol 2005; 243: 539-544
  • 23 Schramm C, Abaza A, Blumenstock G. et al. Limitations of the TheraMon®-microsensor in monitoring occlusion therapy. Acta Ophthalmol 2016; 94: e753-e756
  • 24 Januschowski K, Bechtold TE, Schott TC. et al. Measuring wearing times of glasses and ocular patches using a thermosensor device from orthodontics. Acta Ophthalmol 2013; 91: e635-640
  • 25 Wallace MP, Stewart CE, Moseley MJ. et al. Compliance with occlusion therapy for childhood amblyopia. Invest Ophthalmol Vis Sci 2013; 54: 6158-6166
  • 26 Stewart CE, Stephens DA, Fielder AR. et al. Objectively monitored patching regimens for treatment of amblyopia: randomised trial. BMJ 2007; 335: 707
  • 27 Stewart CE, Fielder AR, Stephens DA. et al. Treatment of unilateral amblyopia: factors influencing visual outcome. Invest Ophthalmol Vis Sci 2005; 46: 3152-3160
  • 28 Stewart CE, Stephens DA, Fielder AR. et al. Modeling dose-response in amblyopia: toward a child-specific treatment plan. Invest Ophthalmol Vis Sci 2007; 48: 2589-2594
  • 29 Gibson EJ. Perceptual learning. Annu Rev Psychol 1963; 14: 29-56
  • 30 Campbell FW, Hess RF, Watson PG. et al. Preliminary results of a physiologically based treatment of amblyopia. Br J Ophthalmol 1978; 62: 748-755
  • 31 Tytla ME, Labow-Daily LS. Evaluation of the CAM treatment for amblyopia: a controlled study. Invest Ophthalmol Vis Sci 1981; 20: 400-406
  • 32 Nyman KG, Singh G, Rydberg A. et al. Controlled study comparing CAM treatment with occlusion therapy. Br J Ophthalmol 1983; 67: 178-180
  • 33 Terrell A. Cambridge stimulator treatment for amblyopia. An evaluation of 80 consecutive cases treated by this method. Aust J Ophthalmol 1981; 9: 121-127
  • 34 Levi DM, Li RW, Silver MA. et al. Sequential perceptual learning of letter identification and „uncrowding“ in normal peripheral vision: Effects of task, training order, and cholinergic enhancement. J Vis 2020; 20: 24
  • 35 Levi DM, Polat U. Neural plasticity in adults with amblyopia. Proc Natl Acad Sci U S A 1996; 93: 6830-6834
  • 36 Polat U, Ma-Naim T, Belkin M. et al. Improving vision in adult amblyopia by perceptual learning. Proc Natl Acad Sci U S A 2004; 101: 6692-6697
  • 37 Polat U, Ma-Naim T, Spierer A. Treatment of children with amblyopia by perceptual learning. Vision Res 2009; 49: 2599-2603
  • 38 Foss AJ. Use of video games for the treatment of amblyopia. Curr Opin Ophthalmol 2017; 28: 276-281
  • 39 Bach M. Dichoptisches Training bei Amblyopie. Ophthalmologe 2016; 113: 304-307
  • 40 Li J, Thompson B, Deng D. et al. Dichoptic training enables the adult amblyopic brain to learn. Curr Biol 2013; 23: R308-R309
  • 41 Hess RF, Mansouri B, Thompson B. A new binocular approach to the treatment of amblyopia in adults well beyond the critical period of visual development. Restor Neurol Neurosci 2010; 28: 793-802
  • 42 Gambacorta C, Nahum M, Vedamurthy I. et al. An action video game for the treatment of amblyopia in children: A feasibility study. Vision Res 2018; 148: 1-14
  • 43 Mezad-Koursh D, Rosenblatt A, Newman H. et al. Home use of binocular dichoptic video content device for treatment of amblyopia: a pilot study. J AAPOS 2018; 22: 134-138.e4
  • 44 Herbison N, MacKeith D, Vivian A. et al. Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system. Br J Ophthalmol 2016; 100: 1511-1516
  • 45 Vedamurthy I, Nahum M, Huang SJ. et al. A dichoptic custom-made action video game as a treatment for adult amblyopia. Vision Res 2015; 114: 173-187
  • 46 Holmes JM, Manh VM, Lazar EL. et al. Effect of a Binocular iPad Game vs. Part-time Patching in Children Aged 5 to 12 Years with Amblyopia: A Randomized Clinical Trial. JAMA Ophthalmol 2016; 134: 1391-1400
  • 47 Manh VM, Holmes JM, Lazar EL. et al. A Randomized Trial of a Binocular iPad Game versus Part-Time Patching in Children Aged 13 to 16 Years with Amblyopia. Am J Ophthalmol 2018; 186: 104-115
  • 48 Tsirlin I, Colpa L, Goltz HC. et al. Behavioral Training as New Treatment for Adult Amblyopia: A Meta-Analysis and Systematic Review. Invest Ophthalmol Vis Sci 2015; 56: 4061-4075
  • 49 Bundesen C, Vangkilde S, Petersen A. Recent developments in a computational theory of visual attention (TVA). Vision Res 2015; 116: 210-218