Diabetologie und Stoffwechsel 2020; 15(06): 487-497
DOI: 10.1055/a-1264-6590
Übersicht

Psychische Komorbiditäten bei Jugendlichen und jungen Erwachsenen mit Typ-1-Diabetes

Mental comorbidity in adolescents and young adults with type 1 diabetes
Agnes Geirhos
1   Klinische Psychologie und Psychotherapie, Institut für Psychologie und Pädagogik, Universität Ulm, Germany
,
Matthias Domhardt
1   Klinische Psychologie und Psychotherapie, Institut für Psychologie und Pädagogik, Universität Ulm, Germany
,
Angela Galler
2   Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Sozialpädiatrisches Zentrum, Pädiatrische Endokrinologie und Diabetologie, Berlin, Germany
,
Christina Reinauer
3   Klinik für Allgemeine Pädiatrie, Neonatologie und Kinderkardiologie, Universitätsklinikum Düsseldorf, Düsseldorf, Germany
,
Petra Warschburger
4   Psychologie, Beratungspsychologie, Universität Potsdam
,
Annabel S. Müller-Stierlin
5   Sektion Gesundheitsökonomie und Versorgungsforschung, Klinik für Psychiatrie und Psychotherapie II, Universität Ulm, Germany
,
Kirsten Minden
6   Klinik für Rheumatologie und klinische Immunologie, Charité – Universitätsmedizin Berlin, kooperatives Mitglied der Freien Universität Berlin, der Humboldt-Universität zu Berlin und des Berliner Instituts für Gesundheitsforschung, Germany
7   Deutsches Rheuma-Forschungszentrum Berlin, Programmbereich Epidemiologie, Germany
,
Svenja Temming
8   Klinik für Pädiatrie mit Schwerpunkt Pneumologie, Immunologie und Intensivmedizin, Charité – Universitätsmedizin Berlin, Germany
,
Reinhard W. Holl
9   ZIBMT, Institut für Epidemiologie und medizinische Biometrie, Universität Ulm, Germany
10   Deutsches Zentrum für Diabetesforschung (DZD), München-Neuherburg, Germany
,
Harald Baumeister
1   Klinische Psychologie und Psychotherapie, Institut für Psychologie und Pädagogik, Universität Ulm, Germany
› Author Affiliations

Zusammenfassung

Jugendliche und junge Erwachsene mit Typ-1-Diabetes sind häufig von komorbiden psychischen Störungen betroffen. Dabei zeigt die Studienlage zur Verbreitung ein heterogenes und inkonsistentes Bild. Diagnose und Behandlung der somatopsychischen Begleiterkrankungen beeinflussen den Behandlungs- und Krankheitsverlauf sowie die Lebensqualität der Betroffenen. Trotzdem wird dies in der klinischen Praxis selten frühzeitig berücksichtigt. Das multizentrische Verbundprojekt COACH verfolgt das Ziel, die Erkennung und Behandlung psychischer Komorbidität für diese Zielgruppe in der bundesweiten Routineversorgung zu optimieren.

Abstract

Adolescents and young adults with type 1 diabetes are often affected by comorbid mental disorders. The evidence on prevalence shows a heterogeneous and inconsistent pattern. Early diagnosis and intervention of the somato-psychological comorbidity have relevant implications for treatment and disease progression as well as quality of life. However, this is still too rarely the case in clinical practice. The multi-center collaborative project COACH aims to optimize the screening for and treatment of mental comorbidity for this target group in nationwide routine care.



Publication History

Received: 02 June 2020

Accepted: 08 September 2020

Article published online:
07 October 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • Literatur

  • 1 Arain M, Haque M, Johal L. et al Maturation of the adolescent brain. Neuropsychiatr Dis Treat 2013; 9: 449-461 . doi:10.2147/NDT.S39776
  • 2 Blakemore SJ, Choudhury S. Brain development during puberty: State of the science: Commentary. Dev Sci 2006; 9: 11-14 . doi:10.1111/j.1467-7687.2005.00456.x
  • 3 Rechenberg K, Whittemore R, Holland M. et al General and diabetes-specific stress in adolescents with type 1 diabetes. 2017; 1-8 DOI: 10.1016/j.diabres.2017.05.003.
  • 4 Ingerski LM, Anderson BJ, Dolan LM. et al Blood glucose monitoring and glycemic control in adolescence:Contribution of diabetes-specific responsibility and familyconflict. 2011; 47: 191-197 . doi:10.1016/j.jadohealth.2010.01.012
  • 5 Kapellen TM, Müther S, Schwandt A. et al Transition to adult diabetes care in Germany – High risk for acute complications and declining metabolic control during the transition phase. Pediatr Diabetes 2018; 19: 1094-1099 . doi:10.1111/pedi.12687
  • 6 Nardi L, Zucchini S, D’Alberton F. et al Quality of life, psychological adjustment and metabolic control in youths with type 1 diabetes: a study with self- and parent-report questionnaires. Pediatr Diabetes 2008; 9: 496-503 . doi:10.1111/j.1399-5448.2008.00414.x
  • 7 Neu A, Bürger-Büsing T, Danne T. et al Diagnostik, Therapie und Verlaufskontrolle des Diabetes mellitus im Kindes- und Jugendalter. Diabetol und Stoffwechsel 2016; 11: 159-169 . doi:10.1055/s-0042-111213
  • 8 Robinson DJ, Coons M, Haensel H. et al 2018 Clinical Practice Guidelines Diabetes and Mental Health. Can J Diabetes 2018; 42: 130-141 . doi:10.1016/j.jcjd.2017.10.031
  • 9 Berufsverband Deutscher Psychologinnen und Psychologen. Die Grossen Volkskrankheiten. Berlin: Deutscher Psychologen Verlag GmbH; 2012
  • 10 Warschburger P. Chronisch kranke Kinder und Jugendliche. Psychosoziale Belastungen und Bewältigungsanforderungen. Göttingen: Hogrefe; 2000
  • 11 Härter M, Baumeister H. Ätiologie psychischer Störungen bei chronischen körperlichen Erkrankungen. In: Härter M, Baumeister H, Bengel J. Hrsg. Psychische Störungen bei körperlichen Erkrankungen. Berlin: Springer; 2007: 1-14
  • 12 Moulton CD, Pickup JC, Ismail K. The link between depression and diabetes: The search for shared mechanisms. Lancet Diabetes Endocrinol 2015; 3: 461-471 . doi:10.1016/S2213-8587(15)00134-5
  • 13 Baumeister H, Kury S, Bengel J. Somatopsychische Komorbidität: Definition und Verständnis. Bundesgesundheitsblatt – Gesundheitsforsch – Gesundheitsschutz; 2011 54. 9-14
  • 14 Northam EA, Matthews LK, Anderson PJ. et al Psychiatric morbidity and health outcome in Type 1 diabetes – Perspectives from a prospective longitudinal study. Diabet Med 2005; 22: 152-157 . doi:10.1111/j.1464-5491.2004.01370.x
  • 15 Bryden KS, Peveler RC, Stein A. et al Clinical and psychological course of diabetes from adolescence to young adulthood: a longitudinal cohort study. Diabetes Care 2001; 24: 1536-1540 . doi:10.2337/diacare.24.9.1536
  • 16 Herzer M, Hood KK. Anxiety symptoms in adolescents with type 1 diabetes: Association with blood glucose monitoring and glycemic control. J Pediatr Psychol 2010; 35: 415-425 . doi:10.1093/jpepsy/jsp063
  • 17 Stahl-Pehe A, Glaubitz L, Bächle C. et al Diabetes distress in young adults with early-onset Type 1 diabetes and its prospective relationship with HbA1c and health status. Diabet Med 2019; 36: 836-846 . doi:10.1111/dme.13931
  • 18 Petrak F, Baumeister H, Skinner TC. et al Depression and diabetes: Treatment and health-care delivery. Lancet Diabetes Endocrinol 2015; 3: 472-485 . doi:10.1016/S2213-8587(15)00045-5
  • 19 Baumeister H. Diagnostik und Indikationsstellung bei psychischen Belastungen und Störungen. In: Bengel J, Mittag O. Hrsg. Psychologie in der medizinischen Rehabilitation. Berlin: Springer; 2016
  • 20 Delamater AM, de Wit M, McDarby V. et al Psychological care of children and adolescents with diabetes. Pediatr Diabetes 2014; 15: 232-244 . doi:10.1111/pedi.12191
  • 21 Baumeister H, Jahed J, Vogel B. et al Diagnostik, Indikation und Behandlung von psychischen Störungen in der medizinischen Rehabilitation (DIBpS): Ein Leitfaden zur Implementierung eines psychodiagnostischen Stufenplans in der medizinischen Rehabilitation. Dtsch Rentenversicherung Bund – Sozialmedizin und Rehabil; 2011: 1-58
  • 22 Korczak DJ, Pereira S, Koulajian K. et al Type 1 diabetes mellitus and major depressive disorder: Evidence for a biological link. Diabetologia 2011; 54: 2483-2493 . doi:10.1007/s00125-011-2240-3
  • 23 Overstreet S, Holmes CS, Dunlap WP. et al Sociodemographic risk factors to intellectual and academic functioning in children with diabetes. Intelligence 1997; 24: 367-380 . doi:10.1016/S0160-2896(97)90066-0
  • 24 Thapar A, Collishaw S, Pine DS. et al Depression in adolescence. Lancet 2012; 379: 1056-1067 . doi:10.1016/S0140-6736(11)60871-4
  • 25 Teasdale S, Mörkl S, Müller-Stierlin AS. Nutritional Psychiatry in the treatment of psychotic disorders: current hypotheses and research challenges. Brain, Behav Immun – Heal 2020; 5: 100070 . doi:10.1016/j.bbih.2020.100070
  • 26 Cabrera SM, Henschel AM, Hessner MJ. Innate inflammation in type 1 diabetes. Transl Res 2016; 167: 214-227 . doi:10.1016/j.trsl.2015.04.011
  • 27 Cairns KE, Yap MBH, Pilkington PD. et al Risk and protective factors for depression that adolescents can modify: A systematic review and meta-analysis of longitudinal studies. J Affect Disord 2014; 169: 61-75 . doi:10.1016/j.jad.2014.08.006
  • 28 Hogendorf AM, Fendler W, Sierosławski J. et al Alcohol and cigarette use among adolescents with type 1 diabetes. Eur J Pediatr 2017; 176: 713-722 . doi:10.1007/s00431-017-2895-y
  • 29 Fulkerson JA, Sherwood NE, Perry CL. et al Depressive symptoms and adolescent eating and health behaviors: A multifaceted view in a population-based sample. Prev Med (Baltim) 2004; 38: 865-875 . doi:10.1016/j.ypmed.2003.12.028
  • 30 Buchberger B, Huppertz H, Krabbe L. et al Symptoms of depression and anxiety in youth with type 1 diabetes: A systematic review and meta-analysis. Psychoneuroendocrinology 2016; 70: 70-84 . doi:10.1016/j.psyneuen.2016.04.019
  • 31 Robert Koch-Institut. Depressive Symptomatik im europäischen Vergleich – Ergebnisse des European Health Interview Survey (EHIS) 2. 2019 4. 62-70 . doi:10.25646/6221
  • 32 Reynolds KA, Helgeson VS. Children with Diabetes Compared to Peers: depressed? Distressed?. Ann Behav Med 2012; 42: 29-41 . doi:10.1007/s12160-011-9262-4
  • 33 Plener PL, Molz E, Berger G. et al Depression, metabolic control, and antidepressant medication in young patients with type 1 diabetes. Pediatr Diabetes 2015; 16: 58-66 . doi:10.1111/pedi.12130
  • 34 La Greca AM, Swales T, Klemp S. et al Adolescents With Diabetes: Gender Differences in Psychosocial Functioning and Glycemic Control. Child Heal Care 1995; 24: 61-78 . doi:10.1207/s15326888chc2401_6
  • 35 Kovacs M, Ho V, Pollock MH. Criterion and predictive validity of the diagnosis of adjustment disorder: a prospective study of youths with new-onset insulin-dependent diabetes mellitus. Am J Psychiatry 1995; 152: 523-528 . doi:10.1176/ajp.152.4.523
  • 36 Icks A, Rosenbauer J, Strassburger K. et al Persistent social disparities in the risk of hospital admission of paediatric diabetic patients in Germany-prospective data from 1277 diabetic children and adolescents. Diabet Med 2007; 24: 440-442 . doi:10.1111/j.1464-5491.2007.02105.x
  • 37 Grey M, Whittemore R, Tamborlane W. Depression in Type 1 diabetes in children natural history and correlates. J Psychosom Res 2002; 53: 907-911 . doi:10.1016/S0022-3999(02)00312-4
  • 38 Thapar A, Collishaw A, Pine DS. et al Depression in adolescence. Lancet 2012; 4: 1056-1067 . doi:10.1016/S0140-6736(11)60871-4
  • 39 Dempster KW, Liu A, Nansel TR. Depression and parenting in youth with type 1 diabetes: Are general and diabetes-specific parenting behaviors associated with depressive symptoms over a 2-year period?. J Behav Med 2019; 42: 842-850 . doi:10.1007/s10865-019-00011-w
  • 40 Tsiouli E, Alexopoulos EC, Stefanaki C. et al Effects of diabetes-related family stress on glycemic control in young patients with type 1 diabetes: Systematic review. Can Fam Physician 2013; 59: 143-149
  • 41 Herzer M, Vesco A, Ingerski LM. et al Explaining the family conflict-glycemic control link through psychological variables in adolescents with type 1 diabetes. J Behav Med 2011; 34: 268-274 . doi:10.1007/s10865-010-9307-3
  • 42 Butler JM, Skinner M, Gelfand D. et al Maternal parenting style and adjustment in adolescents with type I diabetes. J Pediatr Psychol 2007; 32: 1227-1237 . doi:10.1093/jpepsy/jsm065
  • 43 Doric A, Stevanovic D, Knez R. Anxiety and depressive disorders in children and adolescents suffering from diabetes mellitus. Med Flum 2018; 54: 166-176 . doi:10.21860/medflum2018_198208
  • 44 Garrison MM, Katon WJ, Richardson LP. The impact of psychiatric comorbidities on readmissions for diabetes in youth. Diabetes Care 2005; 28: 2150-2154 . doi:10.2337/diacare.28.9.2150
  • 45 Anwar GM, Shennawy HA, Qasim WAA. et al Psychological Disorders in Adolescents with Type 1 Diabetes and their Relation to Metabolic Control. EC Diabetes Metab Res 2018; 2: 3-14
  • 46 Peterson CM, Fischer S, Young-Hyman D. Topical review: A comprehensive risk model for disordered eating in youth with type 1 diabetes. J Pediatr Psychol 2015; 40: 385-390 . doi:10.1093/jpepsy/jsu106
  • 47 Borg H, Gottsater A, Landin-Olsson M. et al High levels of antigen-specific islet antibodies predict future beta-cell failure in patients with onset of diabetes in adult age. J Clin Endocrinol Metab 2001; 86: 3032-3038 . doi:10.1210/jcem.86.7.7658
  • 48 Champaneri S, Wand GS, Malhotra SS. et al Biological basis of depression in adults with diabetes. Curr Diab Rep 2010; 10: 396-405 . doi:10.1007/s11892-010-0148-9
  • 49 Delamater AM, de Wit M, McDarby V. et al ISPAD Clinical Practice Consensus Guidelines 2018: Psychological care of children and adolescents with type 1 diabetes. Pediatr Diabetes 2018; 19: 237-249 . doi:10.1111/pedi.12736
  • 50 Sildorf SM, Breinegaard N, Lindkvist EB. et al Poor Metabolic Control in Children and Adolescents With Type 1 Diabetes and Psychiatric Comorbidity. Diabetes Care 2018; 41: 2289-2296 . doi:10.2337/dc18-0609
  • 51 Starkman H, Fisher K, Pilek NL. et al Listening to adolescents with uncontrolled diabetes, their parents and medical team. Fam Syst Heal 2019; 37: 30-37 . doi:10.1037/fsh0000396
  • 52 Edgar KA, Skinner TC. Illness representations and coping as predictors of emotional well-being in adolescents with type 1 diabetes. J Pediatr Psychol 2003; 28: 485-493 . doi:10.1093/jpepsy/jsg039
  • 53 Jaser SS, Patel N, Xu M. et al Stress and Coping Predicts Adjustment and Glycemic Control in Adolescents with Type 1 Diabetes. Ann Behav Med 2017; 51: 30-38 . doi:10.1007/s12160-016-9825-5
  • 54 Graue M, Wentzel-Larsen T, Bru E. et al The coping styles of adolescents with type 1 diabetes are associated with degree of metabolic control. Diabetes Care 2004; 27: 1313-1317 . doi:10.2337/diacare.27.6.1313
  • 55 Grossman HY, Brink S, Hauser ST. Self-Efficacy in Adolescent Girls and Boys With Insulin-Dependent Diabetes Mellitus. Diabetes Care 1987; 10: 324-329 . doi:10.2337/diacare.10.3.324
  • 56 Kanner S, Hamrin V, Grey M. Depression in adolescents with diabetes. J Child Adolesc Psychiatr Nurs 2003; 16: 15-24 . doi:10.1111/j.1744-6171.2003.tb00342.x
  • 57 Otto C, Barthel D, Klasen F. et al Predictors of self-reported health-related quality of life according to the EQ-5D-Y in chronically ill children and adolescents with asthma, diabetes, and juvenile arthritis: longitudinal results. Qual Life Res 2018; 27: 879-890 . doi:10.1007/s11136-017-1753-8
  • 58 Hilliard ME, Herzer M, Dolan LM. et al Psychological screening in adolescents with type 1 diabetes predicts outcomes one year later. Diabetes Res Clin Pract 2011; 94: 39-44 . doi:10.1016/j.diabres.2011.05.027
  • 59 Helgeson VS, Siminerio L, Escobar O. et al Predictors of metabolic control among adolescents with diabetes: A 4-year longitudinal study. J Pediatr Psychol 2009; 34: 254-270 . doi:10.1093/jpepsy/jsn079
  • 60 Kristensen LJ, Birkebaek NH, Mose AH. et al Multi-informant path models of the influence of psychosocial and treatment-related variables on adherence and metabolic control in adolescents with type 1 diabetes mellitus. PLoS One 2018; 13: 1-20 . doi:10.1371/journal.pone.0204176
  • 61 Snyder LL, Truong YKN, Law JR. Evaluating Substance Use and Insulin Misuse in Adolescents With Type 1 Diabetes. Diabetes Educ 2016; 42: 529-537 . doi:10.1177/0145721716659149
  • 62 Littlefield CH, Craven JL, Rodin GM. et al Relationship of self-efficacy and binging to adherence to diabetes regimen among adolescents. Diabetes Care 1992; 15: 90-94 . doi:10.2337/diacare.15.1.90
  • 63 Rechenberg K, Whittemore R, Grey M. Anxiety in Youth With Type 1 Diabetes. J Pediatr Nurs 2017; 32: 64-71 . doi:10.1016/j.pedn.2016.08.007
  • 64 Shalitin S, Phillip M. Hypoglycemia in type 1 diabetes: a still unresolved problem in the era of insulin analogs and pump therapy. Diabetes Care 2008; 31: 121-124 . doi:10.2337/dc08-s228
  • 65 Clarke W, Jones T, Rewers A. et al Assessment and management of hypoglycemia in children and adolescents with diabetes. Pediatr Diabetes 2009; 10: 134-145 . doi:10.1111/j.1399-5448.2009.00583.x
  • 66 Driscoll KA, Raymond J, Naranjo DPS. Fear of Hypoglycemia in Children and Adolescents and Their Parents with Type 1 Diabetes. Current diabetes reports. Physiol Behav 2016; 16: 77 . doi:10.1007/s11892-016-0762-2
  • 67 Bernstein CM, Stockwell MS, Gallagher MP. et al Mental health issues in adolescents and young adults with type 1 diabetes: Prevalence and impact on glycemic control. Clin Pediatr (Phila) 2013; 52: 10-15 . doi:10.1177/0009922812459950
  • 68 Ravens-Sieberer U, Wille N, Erhart M. et al Prevalence of mental health problems among children and adolescents in Germany: Results of the BELLA study within the national health interview and examination survey. Eur Child Adolesc Psychiatry 2008; 17: 22-33 . doi:10.1007/s00787-008-1003-2
  • 69 Ceylan C, Altay N. Social anxiety levels and associated factors among adolescents with type 1 diabetes compared with healthy peers. J Spec Pediatr Nurs 2017; 22: 1-9 . doi:10.1111/jspn.12172
  • 70 Williams C, Sharpe L, Mullan B. Developmental challenges of adolescents with type 1 diabetes: the role of eating attitudes, family support and fear of negative evaluation. Psychol Health Med 2014; 19: 324-334 . doi:10.1080/13548506.2013.808750
  • 71 Hanna KM, Weaver MT, Stump TE. et al The Relationship of Worry About Hypoglycemia With Diabetes-specific and Typical Youth Behavior Among Emerging Adults With Type 1 Diabetes. Diabetes Educ 2014; 40: 533-542 . doi:10.1177/0145721714528997
  • 72 Martinez K, Frazer SF, Dempster M. et al Psychological factors associated with diabetes self-management among adolescents with Type 1 diabetes: A systematic review. J Health Psychol 2018; 23: 1749-1765 . doi:10.1177/1359105316669580
  • 73 Cobham VE, Hickling A, Kimball H. et al Systematic Review: Anxiety in Children and Adolescents With Chronic Medical Conditions. J Am Acad Child Adolesc Psychiatry 2019; 59: 595-618 . doi:10.1016/j.jaac.2019.10.010
  • 74 Rechenberg K, Grey M, Sadler L. “Anxiety and Type 1 diabetes are like cousins”: The experience of anxiety symptoms in youth with Type 1 diabetes. Res Nurs Heal 2018; 41: 544-554 . doi:10.1002/nur.21913
  • 75 Philippi ST, Cardoso MGL, Koritar P. et al Risk behaviors for eating disorder in adolescents and adults with type 1 diabetes. Rev Bras Psiquiatr 2013; 35: 150-156 . doi:10.1590/1516-4446-2012-0780
  • 76 Hevelke LK, Albrecht C, Busse-Widmann P. et al Prävalenz gestörten Essverhaltens bei Typ 1 Diabetes im Kindes- und Jugendalter: Erfassungsmöglichkeiten und Vergleich mit gesunden Gleichaltrigen – Ergebnisse einer multizentrischen Fragebogenstudie. Psychother Psych Med 2016; 66: 128-135 . doi:10.1055/s-0042-103324
  • 77 Rancourt D, Foster N, Bollepalli S. et al Test of the modified dual pathway model of eating disorders in individuals with type 1 diabetes. Int J Eat Disord 2019; 52: 630-642 . doi:10.1002/eat.23054
  • 78 Caccavale LJ, Nansel TR, Quick V. et al Associations of disordered eating behavior with the family diabetes environment in adolescents with type 1 diabetes. Dev Behav Pediatr 2015; 36: 8-13 . doi:10.1097/DBP.0000000000000116
  • 79 Baechle C, Castillo K, Straßburger K. et al Is disordered eating behavior more prevalent in adolescents with early-onset type 1 diabetes than in their representative peers?. Int J Eat Disord 2014; 47: 342-352 . doi:10.1002/eat.22238
  • 80 Troncone A, Chianese A, Zanfardino A. et al Disordered Eating Behaviors Among Italian Adolescents with Type 1 Diabetes: Exploring Relationships with Parents’ Eating Disorder Symptoms, Externalizing and Internalizing Behaviors, and Body Image Problems. J Clin Psychol Med Settings 2019; DOI: 10.1007/s10880-019-09665-9.
  • 81 Sawyer SM, Afifi RA, Bearinger LH. et al Adolescence: A foundation for future health. Lancet 2012; 379: 1630-1640 . doi:10.1016/S0140-6736(12)60072-5
  • 82 Swanson SA, Crow SJ, Le Grange D. et al Prevalence and correlates of eating disorders in adolescents: Results from the national comorbidity survey replication adolescent supplement. Arch Gen Psychiatry 2011; 68: 714-723 . doi:10.1001/archgenpsychiatry.2011.22
  • 83 Scheuing N, Bartus B, Berger G. et al Clinical characteristics and outcome of 467 patients with a clinically recognized eating disorder identified among 52,215 patients with type 1 diabetes: A multicenter german/austrian study. Diabetes Care 2014; 37: 1581-1589 . doi:10.2337/dc13-2156
  • 84 Wisting L, Bang L, Skrivarhaug T. et al Adolescents with type 1 diabetes – The impact of gender, age, and health-related functioning on eating disorder psychopathology. PLoS One 2015; 10: 1-10 . doi:10.1371/journal.pone.0141386
  • 85 Colton PA, Olmsted MP, Daneman D. et al Depression, disturbed eating behavior, and metabolic control in teenage girls with type 1 diabetes. Pediatr Diabetes 2013; 14: 372-376 . doi:10.1111/pedi.12016
  • 86 Grylli V, Wagner G, Berger G. et al Characteristics of self-regulation in adolescent girls with Type 1 diabetes with and without eating disorders: A cross-sectional study. Psychol Psychother Theory, Res Pract 2010; 83: 289-301 . doi:10.1348/147608309X481180
  • 87 Troncone A, Cascella C, Chianese A. et al Changes in body image and onset of disordered eating behaviors in youth with type 1 diabetes over a five-year longitudinal follow-up. J Psychosom Res 2018; 109: 44-50 . doi:10.1016/j.jpsychores.2018.03.169
  • 88 Mccarvill R, Weaver K. Primary care of female adolescents with type 1 diabetes mellitus and disordered eating. J Adv Nurs 2014; 70: 2005-2018 . doi:10.1111/jan.12384
  • 89 Young V, Eiser C, Johnson B. et al Eating problems in adolescents with Type1 diabetes: A systematic review with meta-analysis. Diabet Med 2013; 30: 189-198 . doi:10.1111/j.1464-5491.2012.03771.x
  • 90 Snell-Bergeon JK, Chartier-Logan C, Maahs DM. et al Adults with type 1 diabetes eat a high-fat atherogenic diet that is associated with coronary artery calcium. Diabetologia 2009; 52: 801-809 . doi:10.1007/s00125-009-1280-4
  • 91 Pinhas-Hamiel O. Eating disorders in adolescents with type 1 diabetes: Challenges in diagnosis and treatment. World J Diabetes 2015; 6: 517 . doi:10.4239/wjd.v6.i3.517
  • 92 Goldman JB, Maclean HM. The Significance of Identity in the Adjustment to Diabetes Among Insulin Users. Diabetes Educ 1998; 24: 741-748 . doi:10.1177/014572179802400610
  • 93 Holt RIG, de Groot M, Golden SH. Diabetes and Depression. Curr Diab Rep 2014; 14: 491 . doi:10.1007/s11892-014-0491-3
  • 94 Hintzpeter B, Klasen F, Schön G. et al Mental health care use among children and adolescents in Germany: results of the longitudinal BELLA study. Eur Child Adolesc Psychiatry 2015; 24: 705-713 . doi:10.1007/s00787-015-0676-6
  • 95 Barry-Menkhaus SA, Stoner AM, MacGregor KL. et al Special Considerations in the Systematic Psychosocial Screening of Youth with Type 1 Diabetes. J Pediatr Psychol 2019; 45: 1-12
  • 96 Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: Validity of a brief depression severity measure. J Gen Intern Med 2001; 16: 606-613 . doi:10.1093/jpepsy/jsz089
  • 97 Kroenke K, Wu J, Yu Z. et al The Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS): Initial Validation in Three Clinical Trials. 2016; 78: 716-727 . doi:10.1097/PSY.0000000000000322
  • 98 Löwe B, Decker O, Müller S. et al Validation and Standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the General Population. Med Care 2008; 46: 266-274 . doi:10.1097/MLR.0b013e318160d093
  • 99 Corrigan P. How stigma interferes with mental health care. Am Psychol 2004; 59: 614-625 . doi:10.1037/0003-066X.59.7.614
  • 100 Reinauer C, Viermann R, Förtsch K. et al Motivational Interviewing as a tool to enhance access to mental health treatment in adolescents with chronic medical conditions and need for psychological support (COACH-MI): Study protocol for a clusterrandomised controlled trial. Trials 2018; 19: 1-9 . doi:10.1186/s13063-018-2997-5
  • 101 Lunkenheimer F, Domhardt M, Geirhos A. et al Effectiveness and cost-effectiveness of guided internet- and mobile-based CBT for adolescents and young adults with chronic somatic conditions and comorbid depression and anxiety symptoms (youthCOACHCD): study protocol for a multicentre randomized controlled trial. Trials 2020; 21: 253 . doi:10.1186/s13063-019-4041-9
  • 102 Domhardt M, Steubl L, Baumeister H. Internet- and Mobile-Based Interventions for Mental and Somatic Conditions in Children and Adolescents. Z Kinder Jugendpsychiatrie Psychother 2020; 48: 33-46 . doi:10.1024/1422-4917/a000625
  • 103 Ebert DD, Zarski AC, Christensen H. et al Internet and computer-based cognitive behavioral therapy for anxiety and depression in youth: A meta-analysis of randomized controlled outcome trials. PLoS One 2015; 10: e0119895 . doi:10.1371/journal.pone.0119895
  • 104 Bendig E, Bauereiß N, Ebert DD. et al Psychologische E-Health Interventionen für Menschen mit chronischen Erkrankungen. Ärztliche Psychother 2018; 13: 229-234
  • 105 Choi SW, Schalet B, Cook KF. et al Establishing a common metric for depressive symptoms: linking the BDI-II, CES-D, and PHQ-9 to PROMIS depression. Psychol Assess 2014; 26: 513-527 . doi:10.1037/a0035768
  • 106 Stockings E, Degenhardt L, Lee YY. et al Symptom screening scales for detecting major depressive disorder in children and adolescents: A systematic review and meta-analysis of reliability, validity and diagnostic utility. J Affect Disord 2015; 174: 447-463 . doi:10.1016/j.jad.2014.11.061
  • 107 McGrady ME, Hood KK. Depressive symptoms in adolescents with type 1 diabetes: associations with longitudinal outcomes. Diabetes Res Clin Pract 2010; 88: e35-e37 . doi:10.1016/j.diabres.2010.03.025
  • 108 Ivarsson T, Lidberg A, Gillberg C. The Birleson Depression Self-Rating Scale (DSRS). Clinical evaluation in an adolescent inpatient population. J Affect Disord 1994; 32: 115-125 . doi:10.1016/0165-0327(94)90069-8
  • 109 Birleson P, Hudson I, Buchanan DG. et al Clinical evaluation of a self-rating scale for depressive disorder in childhood (Depression Self-Rating Scale). J Child Psychol Psychiatry 1987; 28: 43-60 . doi:10.1111/j.1469-7610.1987.tb00651.x
  • 110 Thabrew H, Stasiak K, Bavin LM. et al Validation of the Mood and Feelings Questionnaire (MFQ) and Short Mood and Feelings Questionnaire (SMFQ) in New Zealand help-seeking adolescents. Int J Methods Psychiatr Res 2018; 27: e1610 . doi:10.1002/mpr.1610
  • 111 Eg J, Bilenberg N, Costello EJ. et al Self- and parent-reported depressive symptoms rated by the mood and feelings questionnaire. Psychiatry Res 2018; 268: 419-425 . doi:10.1016/j.psychres.2018.07.016
  • 112 Costello EJ, Angold A. Scales to assess child and adolescent depression: checklists, screens, and nets. J Am Acad Child Adolesc Psychiatry 1988; 27: 726-737 . doi:10.1097/00004583-198811000-00011
  • 113 Shapiro JB, Vesco AT, Weil LEG. et al Psychometric Properties of the Problem Areas in Diabetes: Teen and Parent of Teen Versions. J Pediatr Psychol 2018; 43: 561-571 . doi:10.1093/jpepsy/jsx146
  • 114 Markowitz JT, Volkening LK, Butler DA. et al Youth-Perceived Burden of Type 1 Diabetes: Problem Areas in Diabetes Survey-Pediatric Version (PAID-Peds). J Diabetes Sci Technol 2015; 9: 1080-1085 . doi:10.1177/1932296815583506
  • 115 Bardhoshi G, Duncan K, Erford BT. Psychometric Meta-Analysis of the English Version of the Beck Anxiety Inventory. J Couns Dev 2016; 94: 356-373 . doi:10.1002/jcad.12090
  • 116 Bowers ME, Reider LB, Morales S. et al Differences in Parent and Child Report on the Screen for Child Anxiety-Related Emotional Disorders (SCARED): Implications for Investigations of Social Anxiety in Adolescents. J Abnorm Child Psychol 2019; 48: 561-571 . doi:10.1007/s10802-019-00609-3
  • 117 Kamps JL, Roberts MC, Varela RE. Development of a new fear of hypoglycemia scale: Preliminary results. J Pediatr Psychol 2005; 30: 287-291 . doi:10.1093/jpepsy/jsi038
  • 118 Gonder-Frederick LA, Fisher CD, Ritterband LM. et al Predictors of fear of hypoglycemia in adolescents with type 1 diabetes and their parents. Pediatr Diabetes 2006; 7: 215-222 . doi:10.1111/j.1399-5448.2006.00182.x