Klin Monbl Augenheilkd 2020; 237(04): 427-430
DOI: 10.1055/a-1122-9038
Der interessante Fall
Georg Thieme Verlag KG Stuttgart · New York

Spectral Domain-Optical Coherence Tomography and Optical Coherence Tomography Angiography Findings in a Case of Acute Syphilitic Posterior Placoid Chorioretinitis

Spectral-Domain optische Kohärenztomografie und OCT-Angiografie bei akuter syphilitischer, posteriorer, plakoider Chorioretinitis
Mohamed Sherif
Ophthalmology, Jules Gonin Eye Hospital, Lausanne, Switzerland
Yan Guex-Crosier
Ophthalmology, Jules Gonin Eye Hospital, Lausanne, Switzerland
› Author Affiliations
Further Information

Publication History

received 26 September 2019

accepted 13 February 2020

Publication Date:
24 April 2020 (online)


Ocular syphilis can involve almost any structure of the eye, but posterior uveitis and panuveitis are the most common [1]. Additional manifestations may include anterior uveitis, optic neuropathy, retinal vasculitis, interstitial keratitis, and serous and exudative retinal detachment [2], [3]. Ocular syphilis may lead to decreased visual acuity, including permanent blindness. It can also be associated with neurosyphilis [4]. Both ocular and neurosyphilis can occur at any stage of syphilis, including primary and secondary involvement. Syphilitic uveitis may occur as early as 6 weeks after the primary inoculation and may be the only presenting systemic sign of syphilis. Only a small proportion of syphilitic patients (approximately 5%) present with syphilitic chorioretinitis and 50% of these are seen with bilateral lesions [1].