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DOI: 10.1055/a-0802-5128
Traditionelle Afrikanische Medizin bei Hypertonie – Eine klinische Validierung
Publikationsverlauf
Publikationsdatum:
10. Januar 2019 (online)
Zusammenfassung
Ein großer Teil der Bevölkerung der westafrikanischen Länder verwendet Pflanzen zur gezielten Behandlung von Krankheiten. Im Senegal trinken die Menschen seit über 100 Jahren regelmäßig Tee aus den Blütenkelchen von Hibiscus sabdariffa L. („Bissap“) und aus den Blättern von Combretum micranthum G. Don („Kinkeliba“). Bissap hat in der senegalesischen Küche und allgemein in westafrikanischen Ländern eine herausragende Bedeutung. Kinkeliba ist in vielen afrikanischen Sprachen als „Medizin“ beschrieben, sie gehört zu den wichtigsten Arzneipflanzen der lokalen Flora. Für beide Pflanzen ist eine diuretische Wirkung beschrieben, sie werden für entsprechende Arzneitees verwendet. Die antihypertensive Wirkung von Bissap ist bereits seit den 1990er-Jahren bekannt, vor 4 Jahren wurde sie auch für Kinkeliba beschrieben.
Die bisherigen Untersuchungen, insbesondere eine aktuelle randomisierte vergleichende Studie mit Ramipril, ergaben, dass sowohl Bissap als auch Kinkeliba bei leichter arterieller Hypertonie antihypertensiv wirksam und gut verträglich sind. Größere klinische Studien werden derzeit durchgeführt.
Abstract
Traditional African medicine use in hypertension: A clinical validation
The use of plants for the targeted treatment of diseases is widespread in the population of West Africa. For more than 100 years, the Senegalese have regularly been drinking tea from the calyx and leaves of Hibiscus sabdariffa L. ("Bissap") as well as Combretum micranthum G. Don ("Kinkeliba"). Bissap is of outstanding importance in Senegalese cuisine and generally in West African countries. Similarly, Kinkeliba is described in many African languages as "medicine" and is one of the most important medicinal plants from the local flora. Diuretic effect is attributed to both Bissap and Kinkeliba which have been accordingly used for appropriate medicinal teas. Whereas Bissap’s antihypertensive effect has been known since the 1990s, the same was described for Kinkeliba only 4 years ago. Previous studies including a recent randomized comparative study with Ramipril showed that both Bissap and Kinkeliba have an antihypertensive effect and are well tolerated in mild arterial hypertension. For further validation, larger clinical trials are currently underway.
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