Homeopathy 2015; 104(02): 83-89
DOI: 10.1016/j.homp.2015.01.001
Copyright © The Faculty of Homeopathy 2015

Historical foundations of hormesis

Edward J. Calabrese

Subject Editor:
Further Information

Publication History

Received22 August 2014
revised19 November 2014

accepted27 January 2015

Publication Date:
23 December 2017 (online)

The present paper provides an historical assessment of the concept of hormesis and its relationship to homeopathy and modern medicine. It is argued that the dose–response concept was profoundly influenced by the conflict between homeopathy and traditional medicine and that decisions on which dose–response model to adopt were not based on “science” but rater on historical antipathies. While the historical dispute between homeopathy and traditional medicine has long since subsided, their impact upon the field has been enduring and generally unappreciated, profoundly adversely affecting current drug development, therapeutic strategies and environmental risk assessment strategies and policies.