Placental pathology can be a cause of early severe FGR leading to perinatal morbidity
and mortality with repercussions in future pregnancies. A diagnosis of a placental
lesion on ultrasound should have a detailed clinical and histopathological correlation
for better management in next pregnancy. We present a case report of “placental massive
perivillous fibrinoid degeneration/maternal floor infarction (MPFD)” with very large
avascular placenta. This can lead to fetal growth restriction (FGR) and other complications
for the fetus. It is also known to be associated with antiphospholipid syndrome. Management
with low dose aspirin and low molecular weight heparin achieves good results.
Keywords
Placenta - Massive perivillous fibrinoid degeneration (MPFD) - Maternal floor infarction
(MFI) - Fetal growth restriction (FGR) - Anti phospholipid antibody (APLA) - Low dose
aspirin - Low molecular weight heparin (LMWH)
