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CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2014; 01(01): 45-48
DOI: 10.1007/s40556-014-0002-2
Brief Communication

Amniopatch: Way Forward for Mid-trimester Premature Rupture of Membranes (PROM)

Ashutosh Gupta
1   Department of Fetal Medicine & Medical Genetics, Max Super Speciality West, 1, Press Enclave Road, Saket, 110017, New Delhi, India
,
Anjila Aneja
2   Department of Obstetrics & Gynecology; Minimal Access, Fortis Memorial Research Institute, Gurgaon, Haryana, India
,
Rupam Arora
3   Department of Obstetrics & Gynecology, Max Balaji Hospital, New Delhi, India
,
Renu Sheghal
4   Department of Obstetrics & Gynecology, Artemis Health Institute, Gurgaon, Haryana, India
,
Pooja Gupta
3   Department of Obstetrics & Gynecology, Max Balaji Hospital, New Delhi, India
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Abstract

Fetal membranes are essential for the maintenance of sterile intrauterine milieu for proper fetal growth and development. Chronic infection and inflammation may lead to progressive stretching, hardening of the membranes, making them less elastic and more susceptible to premature rupture of membranes (PROM). PROM is associated with fetal morbidity and mortality which is inversely proportional to the period of gestation. Amniopatch even though still in experimental stages to be an established treatment for PROM, is a formidable treatment modality which has shown to seal the chorioamniotic leak and prolonging the pregnancy with improved fetal outcome. With increasing intrauterine fetal interventions both diagnostic (amniocentesis) and therapeutic (fetoscopy), amniopatch is an option for persistent amniotic fluid leakage which has shown to effectively seal the chorioamniotic leak in about two-third of the cases.

Keywords

Hardening - Elastic - Rupture - Amniopatch - Fetoscopy


Publication History

Received: 17 April 2014

Accepted: 21 May 2014

Article published online:
08 May 2023

© 2014. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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