Summary
In a double blind trial on ten healthy volunteers, the efficacy of a topically applied
mucopolysaccharide polysulphate[*] in the treatment of subcutaneous haematomas was assessed. Standardized haematomas
were induced by subcutaneous injection of a mixture of autogenous blood and 125I-fibrinogen. The absorption of the haematoma, expressed as the removal of the labelled
fibrin(ogen), could thus be objectively measured by the decrease in radioactivity.
The results show an exponential absorption of these haematomas. The absorption time
was reduced to about half compared with placebo, when treated topically with mucopolysaccharide
polysulphate. The difference is statistically highly significant and is also considered
clinically relevant.
Keywords
Haematoma absorption -
125I-fibrinogen - Topical treatment
