Criteria for Screening Diabetes Mellitus Using Serum Fructosamine Level and Fasting Plasma Glucose Level

Abstract:

A screening method using serum fructosamine level and the fasting plasma glucose level was used for screening patients with diabetes mellitus. The criteria for positive tests recommended by the Japanese Society of Multiphasic Health Testing and Services were evaluated. It was found that levels for the serum fructosamine of 290 µmol/l or higher (or, for the fasting plasma glucose of 110 mg/dl or higher) agreed with the standard oral glucose tolerance test in identifying patients with diabetes mellitus in 96.7% of cases, and the serum fructosamine test was simpler and less expensive.

Key-Words

Screening - Diabetes Mellitus - Serum Fructosamine - Plasma Glucose

• REFERENCES

• 1 Kiyose H, Tanaka G. Glucose tolerance screening method using a combination of fasting plasma glucose and hemoglobin A_Ic . J Jpn Diabetes Soc 1987; 30: 325-31.
• 2 Bunn H, Gabbay K, Gallop P. The glycosylation of hemoglobin: relevance to diabetes mellitus. Science 1978; 200: 21-7.
• 3 Baker J, O-Connor J, Metcalf P, Lawson M, Johnson R. Clinical usefulness of estimation of serum fructosamine concentration as a screening test for diabetes mellitus. Br Med J 1983; 287: 863-7.
• 4 Baker J, Metcalf P, Scragg R, Johnson R. Fructosamine Test-Plus, a modified fructosamine assay evaluated. Clin Chem 1991; 37: 552-6.
• 5 European Fructosamine Workshop, Vienna 1989. In: Kraupp O, Sinzinger H. eds. Vienna: Springer Verlag; 1990: 1-96.
• 6 Egashira S, Yamazaki S. A study on the methodology of diabetes mellitus screening in half-day medical checkups. JMHTS 1989; 16: 24-31.
• 7 Hirano K, Suzuki A, Yamasawa I. Screening tests of cases high blood sugar in human dry dock. JMHTS 1990; 17: 49-57.
• 8 Kasezawa N, Suzuki K. The clinical and economical usefulness of determination of serum fructosamine by a new methodology and fasting plasma glucose as a screening test for diabetes mellitus. JMHTS 1991; 18: 290-1.
• 9 Kosaka K, Akanuma Y, Goto Y. A report of the committee for the diagnosis of diabetes mellitus. J Jpn Diab Soc 1982; 25: 859-86.