Summary
Objectives:
Our objectives are: first to investigate the effects of internal cardioversion energies
on the wave fronts propagation in the right atrium immediately after the energy delivery;
second, to track the time course of these effects.
Methods:
The study is based on a measure of organization of the endoatrial electrograms obtained
by a multipolar basket catheter inserted in the right atrium. We estimated the level
of organization by computing the percentage of points laying on the signal baseline
(i.e., number of occurrences, NO). NO values were computed on two-second long windows.
Six non-overlapped windows were selected, one just before and five just after the
last unsuccessful shock.
Results:
Immediately after the shock most of the patients exhibited an increase in the organization
patterns. This increase was more evident in those patients with rather disorganized
patterns and higher energy threshold. This effect fades within a few seconds after
the shock delivery.
Conclusions:
Our data confirm the idea that the electrical shock causes a widespread extinction
of electrical wavefronts, which regenerates after the shock. Since an increase of
organization may lead to a reduction of energy threshold, a potential application
of these findings might consist in the delivery of multiple subthreshold shocks instead
of a single one.
Keywords
Atrial fibrillation - electrogram analysis - internal cardio-version - organization