Can Platelet-Rich Plasma Enhance Anterior Cruciate Ligament and Meniscal Repair?

Ian D. Hutchinson; Scott A. Rodeo; Gabriel S. Perrone; Martha M. Murray

doi:10.1055/s-0034-1387166

The Journal of Knee Surgery, Inhaltsverzeichnis

J Knee Surg 2015; 28(01): 019-028
DOI: 10.1055/s-0034-1387166

Special Focus Section

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Can Platelet-Rich Plasma Enhance Anterior Cruciate Ligament and Meniscal Repair?

Ian D. Hutchinson

¹Department of Orthopaedic Surgery, Wake Forest Baptist Health, Winston Salem, North Carolina

,

Scott A. Rodeo

²Sports Medicine and Shoulder Service, Hospital for Special Surgery, New York, New York

,

Gabriel S. Perrone

³Department of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts

,

Martha M. Murray

³Department of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts

› Institutsangaben

Abstract

The use of platelet-rich plasma (PRP) to improve clinical outcome following a soft tissue injury, regeneration, and repair has been the subject of intense investigation and discussion. This article endeavors to relate clinical and basic science strategies focused on biological augmentation of the healing response in anterior cruciate ligament (ACL) and meniscus repair and replacement using PRP. Therein, a translational feedback loop is created in the literature and targeted towards the entire multidisciplinary team. Ultimately, it is hoped that the theoretical benefits of PRP on soft-tissue interfacial healing will emerge clinically following a careful, focused characterization at the benchtop, and prospective randomized controlled clinical study.

Keywords

ACL - meniscus - PRP - biologics - meniscal repair - ACL reconstruction

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References
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