Abstract
Objective To study the incidence of treated retinopathy of prematurity (ROP) using the revised
U.S. screening guidelines, the rate of missed treatment, and unfavorable anatomic
outcomes over a period of 2 years.
Study Design We reviewed the admission records of premature patients treated at our hospital from
September 2008 to August 2010. Any baby born with a gestational age (GA) of less than
30 weeks or a birth body weight (BW) of less than 2000 g was included in this study.
The ROP screening followed the revised U.S. screening guidelines as presented in 2006.
The indications of treatment for ROP were threshold disease as defined by the Multicenter
Trial of Cryotherapy for Retinopathy of Prematurity study and type 1 prethreshold
ROP as defined by the Early Treatment for Retinopathy of Prematurity Randomized Trial
study.
Results There were 385 infants who were examined for ROP screening during this period. Nineteen
babies (35 eyes) fit the treatment criteria and received treatment. The incidence
of treatment-demand ROP was 4.9% (19/385). Four babies had a birth BW >1500 g (4/19;
21%). Seventeen babies received treatment during their first admission and two babies
received treatment during outpatient follow-up. No baby missed timely treatment. Three
eyes progressed to stage 4/5 after receiving intravitreal bevacizumab treatment. The
success rate after primary bevacizumab was 91% (30/33 eyes).
Conclusion The incidence of treatment-demanding ROP using revised U.S. screening criteria was
4.9%. Teamwork and cooperation are very important to ensure that the highest-quality
care possible is provided to patients in a timely manner.
Keywords
retinopathy of prematurity - screening programs and criteria - gestational age - birth
body weight
