Planta Med 1986; 52(3): 207-210
DOI: 10.1055/s-2007-969124
Full Papers

© Georg Thieme Verlag Stuttgart · New York

Anthracenic Derivatives from Psorospermum febrifugum and their in vitro Cytotoxicities to a Human Colon Carcinoma Cell Line1

Andrew Marston2 , Jean-Charles Chapuis2 , Bernard Sordat3 , Jerome D. Msonthi4 , Kurt Hostettmann2
  • 2Institut de Pharmacognosie et Phytochimie, Ecole de Pharmacie, Université de Lausanne, CH-1005 Lausanne, Switzerland.
  • 3Institut Suisse de Recherches Expérimentales sur le Cancer, CH-1066 Epalinges, Switzerland.
  • 4Department of Chemistry, Chancellor College, University of Malaŵi, Zomba, Malaŵi.
1 Presented in part at the 33rd. Annual Congress on Medicinal Plant Research, Regensburg, F. R. G., 23-27 September, 1985.
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Publikationsverlauf

1985

Publikationsdatum:
26. Februar 2007 (online)

Abstract

Five anthranoid pigments, including a new anthraquinone and a new tetrahydroanthracene, were isolated from the root bark of Psorospermum febrifugum Spach (Guttiferae). Cytotoxic activity of these pigments against the human colon carcinoma cell line Co-115 was investigated. The tetrahydroanthracenes vismione D and acetylvismione D exerted reproducible cytotoxicity in this new in vitro test system.

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