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Synfacts 2015; 11(9): 0906
DOI: 10.1055/s-0034-1378763
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Chk1 Inhibitor GDC-0425

Rezensent(en):
Philip Kocienski
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Publikationsdatum:
18. August 2015 (online)

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Key words

GDC-0425 - checkpoint kinase 1 inhibitors - diazacarbazoles - intramolecular SNAr reaction - cyanation - palladium catalysis