Neuroendocrine Mechanisms of Hypertensive States Developing during Chronic Emotional Stress

Summary

This paper discusses central neuroendocrine mechanisms involved in the development of hypertensive states during emotional stress with reference to the data published in the literature and obtained by the author. The experimental results are used to identify the structural and functional organization of the central nervous system that provides integration of nervous and hormonal factors in the pathogenesis of hypertensive states in response to emotional stress. The hypothesis about the trigger role of posterior hypothalamic nuclei which activate neuroendocrine mechanisms of the development of hypertensive states during emotional stress is documented. Mechanisms of MBRF's participation in the realization of emotional stress are clarified.

Key words

Emotional stress - Hypertension - Endocrine system - Midbrain reticular formation - Posterior hypothalamic nucleus