Analytische und biopharmazeutische Untersuchung trans–isoasaronhaltiger Präparate – 9. Mitteilung über die Wirkstoffe von Asarum europaeum L.¹

Abstract

The present article describes the standardisation of two medicinal substances (radix Asari and extractum rhizomae Asari siccum), and the analysis of the effective substances of Asarum europaeum L. in three forms of application (tinctura rhizomae Asari recentis, dragées with dry extract, and tablets with the isolated effective substance: trans–isoasarone), which correspond to the–three phases of development of phytopharmaka. The results of the examination of the short–time (stress) and long–time (storage) stability of the three forms of application are discussed. Data with respect to dissolution rate and the lipoide distribution of the effective substances of Asarum for the purpose of the control of the „in vitro”–(pharmaceutical)–availability of the different forms of application are published.

Key Word Index

Asarum europaeum L - Phenylpropanoide - Escarol® - Analytik - Haltbarkeit - Biopharmazie