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Synfacts 2009(5): 0550-0550
DOI: 10.1055/s-0028-1088185
DOI: 10.1055/s-0028-1088185
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Ruthenium-Catalyzed Direct Vinylation of Alcohols and Aldehydes
R. L. Patman, M. R. Chaulagain, V. M. Williams, M. J. Krische*
University of Texas at Austin, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
22. April 2009 (online)
Significance
A ruthenium-catalyzed C-C bond-forming transfer hydrogenation protocol is presented in this work. The use of the ruthenium catalyst permits the direct vinylation of primary alcohols or aldehydes in good to very good yields. Internal aliphatic or aromatic alkynes serve as vinyl donors, and a cyclic variation is also demonstrated.