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Synfacts 2008(7): 0701-0701  
DOI: 10.1055/s-2008-1077802
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart · New York

Trehalose-Based Cyclodextrin Analogues

Contributor(s): Timothy M. Swager, Jan M. Schnorr
D. Rodríguez-Lucena, J. M. Benito, E. Álvarez, C. Jaime, J. Perez-Miron, C. Ortiz Mellet*, J. M. García Fernández*
Universidad de Sevilla and Universidad Autónoma de Barcelona, Spain
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Publication History

Publication Date:
20 June 2008 (online)

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Significance

The authors reported the synthesis of the trehalose-based cyclodextrin analogue 6 and its equivalent with two disaccharide subunits. The key step, the coupling of the diamine 4 and the pseudotetrasaccharide 3, yielded 76% of the C 3-symmetric pseudocyclohexasaccharide adduct.