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Synfacts 2008(4): 0437-0437  
DOI: 10.1055/s-2008-1042771
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Hydrogenation of Ketones with SBA-15 Supported Ruthenium Catalyst

Contributor(s): Yasuhiro Uozumi, Takao Osako
G. Liu*, M. Yao, F. Zhang, Y. Gao, H. Li*
Shanghai Normal University, P. R. of China
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Publikationsverlauf

Publikationsdatum:
19. März 2008 (online)

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Significance

A chiral ruthenium catalyst bound to a mesoporous SBA-15 material [Ru-SBA-15/(R,R)-DPEN, 1] was prepared by the postgrafting method. The hydrogenation of aromatic ketones was carried out with the catalyst 1 to give the ­corresponding ethanols in >99% yield and 98.4-99.9% ee (5 examples). In the reaction of aceto­phenone, the catalyst was recovered by filtration and reused seven times. The eighth recycling run gave (R)-1-phenyl-1-ethanol in >99% yield with 93.6% ee.