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Am J Perinatol 1987; 4(2): 131-133
DOI: 10.1055/s-2007-999755
ORIGINAL ARTICLE

© 1987 by Thieme Medical Publishers, Inc.

The Use of Cimetidine in Newborns

Yvan Vandenplas, Liliane Sacre
  • Department of Pediatrics, Academic Hospital, Free University of Brussels, Brussels, Belgium
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Publication History

Publication Date:
04 March 2008 (online)

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ABSTRACT

Cimetidine, a specific H2 antagonist and a potent inhibitor of gastric secretion, was administered in newborns who failed to tolerate oral feeding and presented with abnormal gastric residues accompanied by microscopic or macroscopic high gastrointestinal bleeding. This group of 18 infants was compared to a control group of 15 in similar clinical conditions. After 4 days of treatment with cimetidine (24 mg/kg/day), adapted oral alimentation generally was well tolerated with normal gastric residues. No side effects of the therapy were observed.

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