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Synfacts 2007(7): 0674-0674
DOI: 10.1055/s-2007-968605
DOI: 10.1055/s-2007-968605
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York
Breast Cancer Cell Migration Inhibitor
B. B. Metaferia, L. Chen, H. L. Baker, X.-Y. Huang, C. A. Bewley*
National Institutes of Health, Bethesda and Cornell University, New York, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
22. Juni 2007 (online)
Significance
Synthetic macrolide F is an inhibitor of tumour cell migration of certain cancer cells. This short and efficient synthesis afforded access to five other analogues that were screened against various cancer cell lines.