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Laryngorhinootologie 2009; 88(8): 508-510
DOI: 10.1055/s-0029-1233272
DOI: 10.1055/s-0029-1233272
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Lokale Botulinumneurotoxin-A-Therapie bei tardiver Dyskinesie der Zunge
Local botulinum neurotoxin A therapy in tardive lingual dyskinesiaWeitere Informationen
Publikationsverlauf
Publikationsdatum:
05. August 2009 (online)
Abstract:
Tardive dyskinesia syndromes in the head and neck region may appear as adverse effects of psychopharmacotherapy. They are caused by blockage of central dopamine receptors. Oftentimes, these disorders persist even after discontinuation of the antipsychotic medication, and they are disabling the patients functionally and psychosocially. Medical therapeutic efforts with different psychopharmaceuticals, benzodiazepines or vitamin-E-preparations are frequently unsuccessful. Local application of botulinum neurotoxin A offers a new treatment modality, which can target the overshooting dysfunction directly at the peripheral muscle.