PDF herunterladen
Synfacts 2009(5): 0474-0474  
DOI: 10.1055/s-0028-1088166
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Amphidinolides B1 and B2

Contributor(s): Philip Kocienski, Zofia Komsta
L. Lu, W. Zhang, R. G. Carter*
Oregon State University, Corvallis, USA
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
22. April 2009 (online)

    Lizenzen und Reprints

Significance

Amphidinolides B1 and B2 possess cytotoxic activity against certain cancer lines. This first total synthesis of amphidinolides B1 and B2 focuses on the aldol condensation of fragments F and G. For a correction to the article see: J. Am. Chem. Soc. 2008, 130, 11834.