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Synlett 2009(2): 198-200  
DOI: 10.1055/s-0028-1087511
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© Georg Thieme Verlag Stuttgart ˙ New York

Desulfurizing Difluorination Reaction of Benzyl Sulfides Using IF5

Tadahito Fukuhara, Shoji Hara*
Graduate School of Engineering, Hokkaido University, Sapporo 060-8628, Japan
Fax: +81(11)7066556; e-Mail: shara@eng.hokudai.ac.jp;
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Publication History

Received 10 August 2008
Publication Date:
15 January 2009 (online)

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Abstract

A desulfurizing difluorination reaction of benzyl sulfides having a functional group such as an ester, a ketone, a nitrile, or an amide was performed by a reaction with IF5. Consequently, gem-­difluoro compounds could be obtained selectively.

Key words

fluorination - desulfurization - hypervalent iodine - oxidation - sulfide

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