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Synfacts 2006(9): 0969-0969
DOI: 10.1055/s-2006-949257
DOI: 10.1055/s-2006-949257
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York
PEG-Coated Mesoporous Silica-Supported Pd for the Suzuki-Miyaura Coupling Reaction
Q. Yang, S. Ma*, J. Li, F. Xiao, H. Xiong*
Shanghai Institute of Organic Chemistry and Jilin University, Changchun, P. R. of China
Further Information
Publication History
Publication Date:
23 August 2006 (online)
Significance
Poly(ethylene glycol)-coated SBA-15 mesoporous silica-supported palladium complex 1 was prepared and used as a catalyst in Suzuki-Miyaura coupling reaction. The mesoporous silica-supported palladium complex 1 was prepared by the reaction of Pd(PPh3)4 with poly(ethylene glycol)-coated SBA-15 (eq. 1). The Suzuki coupling reaction of aryl and alkenyl halides with aryl boronic acids took place in water in the presence of 0.001-0.1 mol% palladium of the catalyst 1 to give the coupling products in 66-98% yield (eq. 2). The catalyst 1 was reused without significant loss of catalytic activity (5 reuses, 89-92% yield).