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Synlett 1995; 1995(7): 717-718
DOI: 10.1055/s-1995-5070
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Difluoroalkylation of Carbonyl Compounds with (1,1-Difluoroalkyl)silane Derivatives

Toshiki Hagiwara, Takamasa Fuchikami*
  • *Sagami Chemical Research Center, Nishi-Ohnuma 4-4-1, Sagamihara, Kanagawa 229, Japan
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Publication History

Publication Date:
31 December 2000 (online)

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Difluoromethylation and 1,1-difluoroalkylation of carbonyl compounds were achieved by using (difluoromethyl)- or (1,1-difluoroalkyl)silane derivatives in the presence of fluoride or alkoxide ion source.

Difluoromethylation - Difluoroalkylation - (Difluoromethyl)silanes - (1,1-Diflluoroalkyl)silanes - Carbonyl Compounds