Ni-Catalyzed Reductive Coupling of Alkyl Carbonochloridates and Aryl Iodides

Abstract

A Ni-catalyzed reductive coupling of alkyl carbonochloridates and aryl iodides for the synthesis of aromatic esters has been developed. The present method is a new type of reductive coupling for building Csp²–CO bonds, and it avoids using toxic carbon monoxide gas. It tolerates various aryl iodides, and a coordinating group in alkyl carbonochloridates is key to improving the yield of the reaction.

Key words

Ni catalysis - reductive coupling - aryl ester - Csp²–Csp² coupling - alkyl carbonochloridate

Publication History

Received: 27 April 2023

Accepted after revision: 17 July 2023

Accepted Manuscript online:
18 July 2023

Article published online:
14 September 2023

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