Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration. - Williams,A.J.; Hale,S.L.; Moffett,J.R.; Dave,J.R.; Elliott,P.J.; Adams,J. (J Cereb Blood Flow Metab, 2003)