Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. - Bucay,N.; Sarosi,I.; Dunstan,CR.; Morony,S.; Tarpley,J.; Caparelli,C.; Scully,S.; Tan,HL.; Xu,W.; Lacey,DL.; Boyle,WJ.; Simonet,WS. (Genes Dev, 1998)