Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. - Saxena,R.; Gianniny,L.; Burtt,NP.; Lyssenko,V.; Giuducci,C.; Sjogren,M.; Florez,JC.; Almgren,P.; Isomaa,B.; Orho-Melander,M.; Lindblad,U.; Daly,MJ.; et al. (Diabetes, 2006)