Moderate caloric restriction, but not physiological hyperleptinemia per se, enhances mitochondrial oxidative capacity in rat liver and skeletal muscle-tissue-specific impact on tissue triglyceride content and AKT activation. - Barazzoni,R.; Zanetti,M.; Bosutti,A.; Biolo,G.; Vitali-Serdoz,L.; Stebel,M.; Guarnieri,G. (Endocrinology, 2005)