Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis - Mittra,B.; Saha,A.; Chowdhury,A.R.; Pal,C.; Mandal,S.; Mukhopadhyay,S. (Mol Med, 2000)