A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse. - Matsuda,J.; Vanier,M.T.; Saito,Y.; Tohyama,J.; Suzuki,K.; Suzuki,K. (Hum Mol Genet, 2001)