The lack of nocturnal serum thyrotropin surge in patients with nontoxic nodular goiter may predict the subsequent occurrence of hyperthyroidism. - Bartalena,L.; Martino,E.; Veluzzi,F.; Piga,M.; Petrini,L.; Loviselli,A.; Grasso,L.; Pinchera,A. (J Clin Endocrinol Metab, 1991)