Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex. - Almond,J.B.; Snowden,R.T.; Hunter,A.; Dinsdale,D.; Cain,K.; Cohen,G.M. (Leukemia, 2001)