A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis. - Hanada,K..; Hara,T..; Nishijima,M..; Kuge,O..; Dickson,R..C..; Nagiec,M..M.. (J. Biol. Chem., 1997)