CYP1A2-catalysed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans - Boobis,A.R.; Lynch,A.M.; Murray,S.; de la Torre,R.; Solans,A.; Farre,M.; Segura,J.; Gooderham,N.J.; Davies,D.S. (Cancer Research, 1994)