Destabilization of raf-1 by geldanamycin leads to disruption of the raf- 1-MEK-mitogen-activated protein kinase signalling pathway. - Schulte,T.W.; Blagosklonny,M.V.; Romanova,L.; Mushinski,J.F.; Monia,B.P.; Johnston,J.F.; Nguyen,P.; Trepel,J.; Neckers,L.M. (Mol Cell Biol, 1996)