Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of the hyperfunctioning thyroid adenomas: Identification of additional mutations activating both the cyclic adenosine 3′,5′-monophospate and inositol phosphate-Ca2+ cascades. - Parma,J.; van Sande,J.; Tonacchera,M.; Dumont,J.; Vassart,G. (Mol Endocrinol, 1995)