N-[[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]-N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor. - Sestany,K.; Bellini,F.; Fung,S.; Abraham,N.; Treasurywala,A.; Humber,L.; Duquesne,N.S.; Dvornik,D. (J Med Chem, 1984)