The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor. - ten Cate,H.; Bauer,K.A.; Levi,M.; Edgington,T.S.; Sublett,R.D.; Barzegar,S.; Kass,B.L.; Rosenberg,R.D. (J Clin Invest, 1993)