Epidermolysis bullosa simplex (Dowling-Meara type) is a genetic disease characterized by an abnormal keratin filament network involving keratins K5 and K14. - Ishida-Yamamoto ,A.; McGrath ,J.A.; Chapman ,S.J.; Leigh ,I.M.; Lane ,E.B.; Eady ,R.AJ. (J Invest Dermatol, 1991)