TY - JOUR AU - Philadelpho, Fernanda; Calas, Maria Julia Gregorio; Carneiro, Gracy de Almeida Coutinho; Silveira, Isabela Cunha; Vaz, Andréia Brandão Ribeiro; Nogueira, Adriana Maria Coelho; Bergmann, Anke; Lopes, Flávia Paiva Proença Lobo TI - Comparison of Automated Breast Ultrasound and Hand-Held Breast Ultrasound in the Screening of Dense Breasts TT - Comparação entre a ultrassonografia automatizada e a ultrassonografia convencional no rastreio de mamas densas SN - 0100-7203 SN - 1806-9339 PY - 2021 JO - Rev Bras Ginecol Obstet JF - Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics LA - EN VL - 43 IS - 03 SP - 190 EP - 199 DA - 2021/04/15 KW - dense breast KW - screening KW - hand-held breast ultrasound KW - automated breast ultrasound KW - breast cancer AB - Objective To compare hand-held breast ultrasound (HHBUS) and automated breast ultrasound (ABUS) as screening tool for cancer.Methods A cross-sectional study in patients with mammographically dense breasts was conducted, and both HHBUS and ABUS were performed. Hand-held breast ultrasound was acquired by radiologists and ABUS by mammography technicians and analyzed by breast radiologists. We evaluated the Breast Imaging Reporting and Data System (BI-RADS) classification of the exam and of the lesion, as well as the amount of time required to perform and read each exam. The statistical analysis employed was measures of central tendency and dispersion, frequencies, Student t test, and a univariate logistic regression, through the odds ratio and its respective 95% confidence interval, and with p < 0.05 considered of statistical significance.Results A total of 440 patients were evaluated. Regarding lesions, HHBUS detected 15 (7.7%) BI-RADS 2, 175 (89.3%) BI-RADS 3, and 6 (3%) BI-RADS 4, with 3 being confirmed by biopsy as invasive ductal carcinomas (IDCs), and 3 false-positives. Automated breast ultrasound identified 12 (12.9%) BI-RADS 2, 75 (80.7%) BI-RADS 3, and 6 (6.4%) BI-RADS 4, including 3 lesions detected by HHBUS and confirmed as IDCs, in addition to 1 invasive lobular carcinoma and 2 high-risk lesions not detected by HHBUS. The amount of time required for the radiologist to read the ABUS was statistically inferior compared with the time required to read the HHBUS (p < 0.001). The overall concordance was 80.9%. A total of 219 lesions were detected, from those 70 lesions by both methods, 126 only by HHBUS (84.9% not suspicious by ABUS) and 23 only by ABUS.Conclusion Compared with HHBUS, ABUS allowed adequate sonographic study in supplemental screening for breast cancer in heterogeneously dense and extremely dense breasts. PB - Thieme Revinter Publicações Ltda. DO - 10.1055/s-0040-1722156 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1722156 ER -